Poly(A) polymerase summary

September 6th, 2009

As DNA is transcribed into messenger RNA, it must take certain precautions in order for the messenger RNA to be transported safely out of the nucleus as well as initiating translation in proteins. One of these precautions is the addition of the poly(A) tail at the end of the messenger RNA. After the entire messenger RNA strand has been transcribed, poly(A) polymerase binds to the RNA by magnesium ions and uses ATP to add approximately 250 adenosine nucleotides to the end of the messenger RNA strand. Poly(A) binding proteins then attach to the poly(A) tail to guide it through the remainder of the translation process. Without the poly(A) tail the messenger RNA could potentially be cleaved at the wrong location or form the incorrect or mutated protein.

Megan Roadley

Goodsell, David.  “Poly(A) Polymerase”.  Protein Data Bank. October 2008.  Accessed online 6 September 2009.  http://www.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb106_1.html.

Expectations

August 27th, 2009

I expect to gain a better understanding of how biology and chemistry to support the vital functions of life. As a Biology major, my favorite part of Organic Chemsitry was realizing how important chemistry is to the field of biology. I feel that in order to understand biology more fully, I need to have a strong knowledge in chemistry. I am excited to see the crossroads of the two subject and hope to see my knowledge of biology grow stronger. I also think that by studying chemistry, I will see the reasons behind certain biological processes, which will allow my knowledge of biology to be true knowledge rather than just memorized facts.

Megan Roadley: Cell Biol Lab Exercise #4

October 22nd, 2007

The electronic record of CellBiol Lab Exercise #4 as completed by Megan Roadley

Original post by Megan Roadley via Lablog Autoblog

Megan Roadley: Cell Biol Lab Exercise #3

September 25th, 2007

The electronic record of CellBiol Lab Exercise #3 as completed by Megan Roadley

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Megan Roadley: Cell Biol Lab Exercise #2

September 11th, 2007

The electronic record of CellBiol Lab Exercise #2 as completed by Megan Roadley

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Megan Roadley: Cell Biol Lab Exercise #1

September 4th, 2007

The electronic record of CellBiol Lab Exercise #1 as completed by Megan Roadley

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Lablog Autoblog Test for Megan Roadley

September 2nd, 2007

Congratulations Megan! You have properly setup your blog to receive automatic posts from the CellBiologyOLM through the Lablog Autoblog system. Please do not delete this post.

Original post by Megan Roadley via Lablog Autoblog

Hello world!

September 2nd, 2007

Welcome to UMW Blogs.org. This is your first post. Edit or delete it, then start blogging!